General ENCODEQT Web Tool API

The ENCODEQT module of the ENCODEQueryTools package is a Python wrapper around the ENCODE ChIP-Seq Significance Tool’s API (ENCODEQT API). ENCODEQT expects to receive all data as JSON-formatted text via a POST request to http://encodeweb-elb-726908446.us-west-2.elb.amazonaws.com/encodeqt/hyper/ENCODEQTapi.php.

The ENCODEQT API accepts JSON-formatted input and returns JSON-formatted output. Input should be POSTed to the appropriate server URL (more details below).

For JSON-formatted data to the server, the server expects a single JSON container named “JSONparams” that holds all necessary data as its value. For output from the server, most results will be contained in a single JSON field named “results”. The exception to this is queryType=TFsig, which includes fields for other summary statistics such as the total number of genes analyzed in addition to the results field. Please see the examples below.

JSON Field Descriptions

The ENCODEQT API accepts the following parameters:



elementType

elementType - the type of element to analyze. Accepted values: ‘genes’, ‘transcripts’, ‘pgenes’, and ‘ptranscripts’.

Example:

"elementType" = "genes"

Note

The only valid elementType values for mouse analyses are ‘genes’ and ‘transcripts’.



organism

Organism - the organism to analyze. Accepted values: ‘human’ and ‘mouse’.

Example:

"organism" : "human"


featureType

featureType - the feature to be used for the center of the analysis window. Accepted values: ‘TSS’, ‘TTS’, and ‘Genic’.

Example:

"featureType" : "TSS"


upstream

upstream - the value to use for the upstream pad.

Example:

"upstream" : -4

Note

The API expects this value to follow the following formula: ceiling(numberOfBasePairs / 500) * -1. The Python library converts raw basepair counts according to this formula. For other implementations, this conversion must be done manually. -1 corresponds to a 500 bp pad, -2 to a 1,000 bp pad, etc.



downstream

downstream - the value to use for the downstream pad.

Example:

"downstream" : 4

Note

The API expects this value to follow the following formula: ceiling(numberOfBasePairs / 500). The Python library converts raw basepair counts according to this formula. For other implementations, this conversion must be done manually. 1 corresponds to a 500 bp pad, 2 to a 1,000 bp pad, etc.



symbolType

symbolType - the type of symbol to be used as the gene/transcript IDs. Accepted values: ‘symbol’, ‘ensembl’, ‘entrez’, and ‘havana’.

Example:

"symbolType" : "symbol"

Warning

Not all symbol types are valid for all organism and featureType combinations. ‘entrez’ is an invalid symbolType for transcript or ptranscript analyses. ‘havana’ is only valid for human analyses.

Note

‘symbol’ refers to HGNC gene or transcript symbols.



symbolList

symbolList - an array of arrays containing the lists of IDs to use as the foreground.

Example (single foreground list - truncated):

"symbolList" : [["ABT1","ACVR1","ADAM12","ADD3","AGGF1"]]

Example (multiple foreground lists - truncated):

"symbolList" : [["ABT1","ACVR1","ADAM12","ADD3","AGGF1"],["ANKRD28","AP4S1","APBB2","APOBR","AQP2","ARHGAP44","ARID1A","ARID4A"GGF1"]]


listNames

listNames - an array of strings to use as labels for each foreground list.

Note

The number of elements in this array must correspond to the number of lists provided in symbolList. This parameter is optional for queries that only use a single foreground list (a default value of “List1” will be used).

Example:

"listNames" : ["AAAYRNCTG_Motifs"]


cellLines

cellLines - an array of cell types to use for the query. Labels must correspond to the labels used in the ENCODEQT database (see the ENCODE Cell Types webpage).

Example (pooling all cell lines):

"cellLines : ['all']

Example (pooling specific cell lines):

"cellLines : ['Helas3','K562']

Note

For queries that pool all cell lines, listNames should be a single-element array containing the value “all”.



backgroundList

backgroundList - an array containing the gene/transcript IDs to use as the background.

Example (truncated):

"backgroundList" : ["ABT1","ACVR1","ADAM12","ADD3","AGGF1"]

Warning

To use the set of all genes as the background, this parameter should NOT be passed to the API!



queryType

queryType - the type of query to run. This parameter determines which function will be run server-side. Accepted values are ‘TFsig’, ‘allGenes’, ‘listGenes’, ‘validateTF’, ‘validateCellLine’, ‘fuzzyFactorSearch’, ‘fuzzyCellLineSearch’, ‘getTFsAndCellLines’, and ‘geneCheck’.

"queryType" : "TFsig"


targetFactor

targetFactor - the label of the transcription factor of interest.

Example:

"targetFactor" : "Suz12"


targetCellLine

targetCellLine - the label of the cell type of interest.

Example:

"targetCellLine" : "K562"

Note

Descriptions and examples of each queryType appear below.



Example Queries

TFsig

TFsig - determines significantly enriched transcription factors given a list of genes or transcripts.

Note

Required parameters: featureType, cellLines, symbolList, downstream, upstream, elementType, organism, symbolType, queryType

Note

Optional parameters: backgroundList, listNames (optional when only one symbolList is provided)

Input Example:

{
   "JSONparams":{
      "featureType":"TSS",
      "listNames":[
         "AAYRNCTG_Motifs"
      ],
      "cellLines":[
         "all"
      ],
      "symbolList":[
         [
            "ABT1",
            "ACVR1",
            "ADAM12",
            "ADD3",
            "AGGF1",
            "ANKRD12",
            "ANKRD28",
            "AP4S1",
            "APBB2",
            "APOBR",
            "AQP2",
            "ARHGAP44",
            "ARID1A",
            "ARID4A",
            "ARPC2",
            "ARSG",
            "ARX",
            "ASB4",
            "ASPH",
            "ATOH8",
            "ATP1A2",
            "ATP5L",
            "ATPIF1",
            "AXDND1",
            "B4GALT6",
            "BAI3",
            "BAMBI",
            "BCL2L1",
            "BCL9",
            "BMPR1B",
            "BMX",
            "BRSK2",
            "BTBD3",
            "BUB3",
            "C11ORF84",
            "C11ORF92",
            "C12ORF65",
            "C13ORF30",
            "C14ORF1",
            "C15ORF26",
            "C17ORF28",
            "C20ORF197",
            "C3ORF19",
            "C6ORF138",
            "CA3",
            "CACNA2D3",
            "CACNB2",
            "CAPN1",
            "CAPZA1",
            "CASQ2",
            "CBX2",
            "CCNJ",
            "CCNY",
            "CDC23",
            "CDH2",
            "CER1",
            "CHRM1",
            "CITED2",
            "CLDN5",
            "CLTC",
            "CMKLR1",
            "CNTLN",
            "CNTN1",
            "COCH",
            "COL12A1",
            "COL1A2",
            "COL4A5",
            "COL4A6",
            "COLEC10",
            "CRAT",
            "CRH",
            "CRKL",
            "CRYGD",
            "CRYGS",
            "CSNK1A1",
            "CSRNP3",
            "CSTF3",
            "CYBRD1",
            "DAAM1",
            "DBNDD2",
            "DCAKD",
            "DDAH2",
            "DDX4",
            "DEF6",
            "DENND4A",
            "DGKB",
            "DHH",
            "DHRS4",
            "DHRS4L2",
            "DIDO1",
            "DMD",
            "DMRT1",
            "DNAJA2",
            "DNAJB3",
            "DNAJB4",
            "DSCAML1",
            "DUSP4",
            "DYNC1I1",
            "DYRK1A",
            "EDA",
            "EFNA1",
            "EGFLAM",
            "EIF5",
            "EMX2",
            "EPC1",
            "EPHA7",
            "ERBB4",
            "ERRFI1",
            "ESRP2",
            "ESRRB",
            "ESRRG",
            "EYA1",
            "FAM49A",
            "FAM83F",
            "FCER1A",
            "FGD4",
            "FGF10",
            "FGF12",
            "FGFR1",
            "FGFR1OP2",
            "FIZ1",
            "FKRP",
            "FMNL3",
            "FNDC9",
            "FOXA1",
            "FOXG1",
            "FOXO4",
            "FOXP2",
            "FSIP2",
            "FST",
            "GABRA3",
            "GDNF",
            "GFI1",
            "GGNBP2",
            "GJB4",
            "GLDN",
            "GNAQ",
            "GPR85",
            "GPRC5D",
            "GRIN2B",
            "H3F3A",
            "HDAC8",
            "HESX1",
            "HEXIM2",
            "HGF",
            "HIC2",
            "HIP1R",
            "HN1",
            "HOXA10",
            "HOXA5",
            "HOXB8",
            "HPSE2",
            "HSD3B7",
            "ICAM4",
            "ID1",
            "IGF1",
            "IL1RAPL1",
            "INHBC",
            "IP6K2",
            "ITGA10",
            "ITGA8",
            "JPH1",
            "KANK2",
            "KCNIP2",
            "KCNK5",
            "KCNN3",
            "KCNQ1DN",
            "KIAA0182",
            "KITLG",
            "KLF5",
            "KLHDC10",
            "KLHL20",
            "KLHL3",
            "LARS2",
            "LENG9",
            "LHFP",
            "LHX9",
            "LMO7",
            "LOC151534",
            "LRP5",
            "LRRC4",
            "LRRN4CL",
            "LTBP1",
            "MAML1",
            "MANF",
            "MAP2",
            "MAP3K5",
            "MAP6",
            "MEIS1",
            "MGAT1",
            "MGAT4A",
            "MID1",
            "MLL",
            "MOAP1",
            "MPP6",
            "MPPED2",
            "MRPL13",
            "MTA2",
            "MTBP",
            "MYF6",
            "MYH1",
            "MYH10",
            "MYO18A",
            "NAGLU",
            "NAPB",
            "NAV2",
            "NAV3",
            "NCDN",
            "NDNF",
            "NDST4",
            "NDUFS4",
            "NEK1",
            "NEK2",
            "NFATC4",
            "NFYB",
            "NMI",
            "NMT1",
            "NR2F1",
            "NRG1",
            "NTRK2",
            "NUP54",
            "NXPH4",
            "OMA1",
            "OMG",
            "OR2L13",
            "OTX2",
            "PACRG",
            "PAPD5",
            "PARK2",
            "PART1",
            "PCDH17",
            "PCDH18",
            "PCF11",
            "PCYT1B",
            "PDGFB",
            "PDGFRA",
            "PDLIM2",
            "PDS5B",
            "PDZRN4",
            "PFN2",
            "PHC2",
            "PHEX",
            "PHF1",
            "PHF15",
            "PHF6",
            "PHOX2B",
            "PLAGL2",
            "PLEC",
            "PLEKHM1",
            "PLP2",
            "PMCH",
            "PMCHL1",
            "PODXL2",
            "POFUT1",
            "POU2AF1",
            "POU4F1",
            "PPAP2B",
            "PPP1R9B",
            "PPP2R3A",
            "PPP2R4",
            "PPP2R5E",
            "PPP3CA",
            "PRELP",
            "PRKCG",
            "PRKCQ",
            "PROK2",
            "PTH1R",
            "PXN",
            "R3HDM1",
            "RAB30",
            "RAB5B",
            "RAB5C",
            "RAPGEF4",
            "RBMS3",
            "RGS17",
            "RNF146",
            "ROBO4",
            "ROR1",
            "RPLP0",
            "RTN1",
            "RUFY3",
            "S1PR2",
            "SCN3B",
            "SCN5A",
            "SCN8A",
            "SCOC",
            "SDCBP",
            "SEMA6D",
            "SEPT7",
            "SESN3",
            "SGCD",
            "SH2D6",
            "SHC3",
            "SHCBP1L",
            "SIPA1",
            "SIRPA",
            "SLC26A6",
            "SLC4A1",
            "SLC6A1",
            "SMARCA2",
            "SNX9",
            "SORBS2",
            "SOX12",
            "SOX21",
            "SOX30",
            "SOX5",
            "SPOCK2",
            "SPTLC2",
            "SRGAP2",
            "SRSF8",
            "SSBP2",
            "ST7L",
            "STAC3",
            "STAG1",
            "STAG2",
            "STC2",
            "STRN3",
            "STRN4",
            "TAS1R2",
            "TEF",
            "TFAP4",
            "TFDP2",
            "TM2D3",
            "TMEM182",
            "TMEM27",
            "TMEM69",
            "TMSB4X",
            "TMSB4XP1",
            "TMSL3",
            "TMSL6",
            "TNFAIP8",
            "TNS1",
            "TNXB",
            "TP53INP2",
            "TRDN",
            "TREML1",
            "TRIM28",
            "TRIM68",
            "TRIM8",
            "TRIML1",
            "TRPS1",
            "TSC22D3",
            "TSPAN7",
            "TSPY26P",
            "TSSK3",
            "TTC17",
            "TUSC2",
            "UBE2W",
            "UBXN10",
            "USP1",
            "VDR",
            "VIP",
            "VKORC1L1",
            "VWA5A",
            "WBP1",
            "WNT2B",
            "WT1",
            "WT1-AS",
            "XRCC1",
            "ZADH2",
            "ZBTB11",
            "ZFP91",
            "ZFPM2",
            "ZIC1",
            "ZIC4",
            "ZMAT3",
            "ZNF238",
            "ZNF296",
            "ZNF503",
            "ZNF521",
            "ZNF524",
            "ZNF654",
            "ZNF687",
            "ZNF710"
         ]
      ],
      "downstream":4,
      "upstream":-4,
      "elementType":"genes",
      "organism":"human",
      "queryType":"TFsig",
      "symbolType":"symbol"
   }
}


allGenes

allGenes - get all genes/transcripts in our database with a transcription factor target window intersection.

Note

Required parameters: featureType, cellLines, symbolType, downstream, upstream, elementType, organism, queryType, factorTarget

Input Example:

{
   "JSONparams":{
      "featureType":"TSS",
      "cellLines":[
         "all"
      ],
      "symbolType":"symbol",
      "downstream":4,
      "upstream":-4,
      "elementType":"genes",
      "organism":"human",
      "queryType":"allGenes",
      "factorTarget":"Suz12"
   }
}


listGenes

listGenes - get all genes/transcripts in symbolList with a transcription factor target window intersection.

Note

Required parameters: featureType, downstream, upstream, symbolType, factorTarget, cellLines, elementType, organism, queryType, symbolList.

Input Example:

{
   "JSONparams":{
      "featureType":"TSS",
      "downstream":4,
      "symbolType":"symbol",
      "upstream":-4,
      "targetList":"List1",
      "factorTarget":"Suz12",
      "cellLines":[
        "all"
      ],
      "elementType":"genes",
      "organism":"human",
      "queryType":"listGenes",
      "symbolList":[
         [
            "ABT1",
            "ACVR1",
            "ADAM12",
            "ADD3",
            "AGGF1",
            "ANKRD12",
            "ANKRD28",
            "AP4S1",
            "APBB2",
            "APOBR",
            "AQP2",
            "ARHGAP44",
            "ARID1A",
            "ARID4A",
            "ARPC2",
            "ARSG",
            "ARX",
            "ASB4",
            "ASPH",
            "ATOH8",
            "ATP1A2",
            "ATP5L",
            "ATPIF1",
            "AXDND1",
            "B4GALT6",
            "BAI3",
            "BAMBI",
            "BCL2L1",
            "BCL9",
            "BMPR1B",
            "BMX",
            "BRSK2",
            "BTBD3",
            "BUB3",
            "C11ORF84",
            "C11ORF92",
            "C12ORF65",
            "C13ORF30",
            "C14ORF1",
            "C15ORF26",
            "C17ORF28",
            "C20ORF197",
            "C3ORF19",
            "C6ORF138",
            "CA3",
            "CACNA2D3",
            "CACNB2",
            "CAPN1",
            "CAPZA1",
            "CASQ2",
            "CBX2",
            "CCNJ",
            "CCNY",
            "CDC23",
            "CDH2",
            "CER1",
            "CHRM1",
            "CITED2",
            "CLDN5",
            "CLTC",
            "CMKLR1",
            "CNTLN",
            "CNTN1",
            "COCH",
            "COL12A1",
            "COL1A2",
            "COL4A5",
            "COL4A6",
            "COLEC10",
            "CRAT",
            "CRH",
            "CRKL",
            "CRYGD",
            "CRYGS",
            "CSNK1A1",
            "CSRNP3",
            "CSTF3",
            "CYBRD1",
            "DAAM1",
            "DBNDD2",
            "DCAKD",
            "DDAH2",
            "DDX4",
            "DEF6",
            "DENND4A",
            "DGKB",
            "DHH",
            "DHRS4",
            "DHRS4L2",
            "DIDO1",
            "DMD",
            "DMRT1",
            "DNAJA2",
            "DNAJB3",
            "DNAJB4",
            "DSCAML1",
            "DUSP4",
            "DYNC1I1",
            "DYRK1A",
            "EDA",
            "EFNA1",
            "EGFLAM",
            "EIF5",
            "EMX2",
            "EPC1",
            "EPHA7",
            "ERBB4",
            "ERRFI1",
            "ESRP2",
            "ESRRB",
            "ESRRG",
            "EYA1",
            "FAM49A",
            "FAM83F",
            "FCER1A",
            "FGD4",
            "FGF10",
            "FGF12",
            "FGFR1",
            "FGFR1OP2",
            "FIZ1",
            "FKRP",
            "FMNL3",
            "FNDC9",
            "FOXA1",
            "FOXG1",
            "FOXO4",
            "FOXP2",
            "FSIP2",
            "FST",
            "GABRA3",
            "GDNF",
            "GFI1",
            "GGNBP2",
            "GJB4",
            "GLDN",
            "GNAQ",
            "GPR85",
            "GPRC5D",
            "GRIN2B",
            "H3F3A",
            "HDAC8",
            "HESX1",
            "HEXIM2",
            "HGF",
            "HIC2",
            "HIP1R",
            "HN1",
            "HOXA10",
            "HOXA5",
            "HOXB8",
            "HPSE2",
            "HSD3B7",
            "ICAM4",
            "ID1",
            "IGF1",
            "IL1RAPL1",
            "INHBC",
            "IP6K2",
            "ITGA10",
            "ITGA8",
            "JPH1",
            "KANK2",
            "KCNIP2",
            "KCNK5",
            "KCNN3",
            "KCNQ1DN",
            "KIAA0182",
            "KITLG",
            "KLF5",
            "KLHDC10",
            "KLHL20",
            "KLHL3",
            "LARS2",
            "LENG9",
            "LHFP",
            "LHX9",
            "LMO7",
            "LOC151534",
            "LRP5",
            "LRRC4",
            "LRRN4CL",
            "LTBP1",
            "MAML1",
            "MANF",
            "MAP2",
            "MAP3K5",
            "MAP6",
            "MEIS1",
            "MGAT1",
            "MGAT4A",
            "MID1",
            "MLL",
            "MOAP1",
            "MPP6",
            "MPPED2",
            "MRPL13",
            "MTA2",
            "MTBP",
            "MYF6",
            "MYH1",
            "MYH10",
            "MYO18A",
            "NAGLU",
            "NAPB",
            "NAV2",
            "NAV3",
            "NCDN",
            "NDNF",
            "NDST4",
            "NDUFS4",
            "NEK1",
            "NEK2",
            "NFATC4",
            "NFYB",
            "NMI",
            "NMT1",
            "NR2F1",
            "NRG1",
            "NTRK2",
            "NUP54",
            "NXPH4",
            "OMA1",
            "OMG",
            "OR2L13",
            "OTX2",
            "PACRG",
            "PAPD5",
            "PARK2",
            "PART1",
            "PCDH17",
            "PCDH18",
            "PCF11",
            "PCYT1B",
            "PDGFB",
            "PDGFRA",
            "PDLIM2",
            "PDS5B",
            "PDZRN4",
            "PFN2",
            "PHC2",
            "PHEX",
            "PHF1",
            "PHF15",
            "PHF6",
            "PHOX2B",
            "PLAGL2",
            "PLEC",
            "PLEKHM1",
            "PLP2",
            "PMCH",
            "PMCHL1",
            "PODXL2",
            "POFUT1",
            "POU2AF1",
            "POU4F1",
            "PPAP2B",
            "PPP1R9B",
            "PPP2R3A",
            "PPP2R4",
            "PPP2R5E",
            "PPP3CA",
            "PRELP",
            "PRKCG",
            "PRKCQ",
            "PROK2",
            "PTH1R",
            "PXN",
            "R3HDM1",
            "RAB30",
            "RAB5B",
            "RAB5C",
            "RAPGEF4",
            "RBMS3",
            "RGS17",
            "RNF146",
            "ROBO4",
            "ROR1",
            "RPLP0",
            "RTN1",
            "RUFY3",
            "S1PR2",
            "SCN3B",
            "SCN5A",
            "SCN8A",
            "SCOC",
            "SDCBP",
            "SEMA6D",
            "SEPT7",
            "SESN3",
            "SGCD",
            "SH2D6",
            "SHC3",
            "SHCBP1L",
            "SIPA1",
            "SIRPA",
            "SLC26A6",
            "SLC4A1",
            "SLC6A1",
            "SMARCA2",
            "SNX9",
            "SORBS2",
            "SOX12",
            "SOX21",
            "SOX30",
            "SOX5",
            "SPOCK2",
            "SPTLC2",
            "SRGAP2",
            "SRSF8",
            "SSBP2",
            "ST7L",
            "STAC3",
            "STAG1",
            "STAG2",
            "STC2",
            "STRN3",
            "STRN4",
            "TAS1R2",
            "TEF",
            "TFAP4",
            "TFDP2",
            "TM2D3",
            "TMEM182",
            "TMEM27",
            "TMEM69",
            "TMSB4X",
            "TMSB4XP1",
            "TMSL3",
            "TMSL6",
            "TNFAIP8",
            "TNS1",
            "TNXB",
            "TP53INP2",
            "TRDN",
            "TREML1",
            "TRIM28",
            "TRIM68",
            "TRIM8",
            "TRIML1",
            "TRPS1",
            "TSC22D3",
            "TSPAN7",
            "TSPY26P",
            "TSSK3",
            "TTC17",
            "TUSC2",
            "UBE2W",
            "UBXN10",
            "USP1",
            "VDR",
            "VIP",
            "VKORC1L1",
            "VWA5A",
            "WBP1",
            "WNT2B",
            "WT1",
            "WT1-AS",
            "XRCC1",
            "ZADH2",
            "ZBTB11",
            "ZFP91",
            "ZFPM2",
            "ZIC1",
            "ZIC4",
            "ZMAT3",
            "ZNF238",
            "ZNF296",
            "ZNF503",
            "ZNF521",
            "ZNF524",
            "ZNF654",
            "ZNF687",
            "ZNF710"
         ]
      ]
   }
}


validateTF

validateTF - checks if the provided transcription factor label is valid.

Note

Required parameters: targetFactor, organism, queryType.

Example:

{
   "JSONparams":{
      "targetFactor":"Suz12",
      "organism":"human",
      "queryType":"validateTF"
   }
}


validateCellLines

validateCellLine - checks if the provided cell type label is valid.

Note

Required parameters: organism, queryType, targetCellLine.

Example:

{
   "JSONparams":{
      "organism":"human",
      "queryType":"validateCellLine",
      "targetCellLine":"K562"
   }
}


fuzzyFactorSearch

fuzzyFactorSearch - checks the provided string against valid transcription factor labels and returns possible matches.

Note

Required parameters: targetFactor, organism, queryType.

Example:

{
   "JSONparams":{
      "targetFactor":"Pol2",
      "organism":"human",
      "queryType":"fuzzyFactorSearch"
   }
}


fuzzyCellLineSearch

fuzzyCellLineSearch - checks the provided string against valid cell type labels and returns possible matches.

Note

Required parameters: organism, queryType, targetCellLine.

Example:

{
   "JSONparams":{
      "organism":"human",
      "queryType":"fuzzyCellLineSearch",
      "targetCellLine":"He"
   }
}


getTFsAndCellLines

getTFsAndCellLines - returns all valid transcription factor/cell line combinations.

Note

Required parameters: organism, queryType.

Example:

{
   "JSONparams":{
      "organism":"human",
      "queryType":"getTFsAndCellLines"
   }
}


geneCheck

geneCheck - checks if the provided gene IDs are valid in our database.

Note

Required parameters: symbolList, organism, elementType, queryType, symbolType.

Example:

{
   "JSONparams":{
      "symbolList":[
         [
            "ABT1",
            "ACVR1",
            "ADAM12",
            "ADD3",
            "AGGF1",
            "ANKRD12",
            "ANKRD28",
            "AP4S1",
            "APBB2",
            "APOBR",
            "AQP2",
            "ARHGAP44",
            "ARID1A",
            "ARID4A",
            "ARPC2",
            "ARSG",
            "ARX",
            "ASB4",
            "ASPH",
            "ATOH8",
            "ATP1A2",
            "ATP5L",
            "ATPIF1",
            "AXDND1",
            "B4GALT6",
            "BAI3",
            "BAMBI",
            "BCL2L1",
            "BCL9",
            "BMPR1B",
            "BMX",
            "BRSK2",
            "BTBD3",
            "BUB3",
            "C11ORF84",
            "C11ORF92",
            "C12ORF65",
            "C13ORF30",
            "C14ORF1",
            "C15ORF26",
            "C17ORF28",
            "C20ORF197",
            "C3ORF19",
            "C6ORF138",
            "CA3",
            "CACNA2D3",
            "CACNB2",
            "CAPN1",
            "CAPZA1",
            "CASQ2",
            "CBX2",
            "CCNJ",
            "CCNY",
            "CDC23",
            "CDH2",
            "CER1",
            "CHRM1",
            "CITED2",
            "CLDN5",
            "CLTC",
            "CMKLR1",
            "CNTLN",
            "CNTN1",
            "COCH",
            "COL12A1",
            "COL1A2",
            "COL4A5",
            "COL4A6",
            "COLEC10",
            "CRAT",
            "CRH",
            "CRKL",
            "CRYGD",
            "CRYGS",
            "CSNK1A1",
            "CSRNP3",
            "CSTF3",
            "CYBRD1",
            "DAAM1",
            "DBNDD2",
            "DCAKD",
            "DDAH2",
            "DDX4",
            "DEF6",
            "DENND4A",
            "DGKB",
            "DHH",
            "DHRS4",
            "DHRS4L2",
            "DIDO1",
            "DMD",
            "DMRT1",
            "DNAJA2",
            "DNAJB3",
            "DNAJB4",
            "DSCAML1",
            "DUSP4",
            "DYNC1I1",
            "DYRK1A",
            "EDA",
            "EFNA1",
            "EGFLAM",
            "EIF5",
            "EMX2",
            "EPC1",
            "EPHA7",
            "ERBB4",
            "ERRFI1",
            "ESRP2",
            "ESRRB",
            "ESRRG",
            "EYA1",
            "FAM49A",
            "FAM83F",
            "FCER1A",
            "FGD4",
            "FGF10",
            "FGF12",
            "FGFR1",
            "FGFR1OP2",
            "FIZ1",
            "FKRP",
            "FMNL3",
            "FNDC9",
            "FOXA1",
            "FOXG1",
            "FOXO4",
            "FOXP2",
            "FSIP2",
            "FST",
            "GABRA3",
            "GDNF",
            "GFI1",
            "GGNBP2",
            "GJB4",
            "GLDN",
            "GNAQ",
            "GPR85",
            "GPRC5D",
            "GRIN2B",
            "H3F3A",
            "HDAC8",
            "HESX1",
            "HEXIM2",
            "HGF",
            "HIC2",
            "HIP1R",
            "HN1",
            "HOXA10",
            "HOXA5",
            "HOXB8",
            "HPSE2",
            "HSD3B7",
            "ICAM4",
            "ID1",
            "IGF1",
            "IL1RAPL1",
            "INHBC",
            "IP6K2",
            "ITGA10",
            "ITGA8",
            "JPH1",
            "KANK2",
            "KCNIP2",
            "KCNK5",
            "KCNN3",
            "KCNQ1DN",
            "KIAA0182",
            "KITLG",
            "KLF5",
            "KLHDC10",
            "KLHL20",
            "KLHL3",
            "LARS2",
            "LENG9",
            "LHFP",
            "LHX9",
            "LMO7",
            "LOC151534",
            "LRP5",
            "LRRC4",
            "LRRN4CL",
            "LTBP1",
            "MAML1",
            "MANF",
            "MAP2",
            "MAP3K5",
            "MAP6",
            "MEIS1",
            "MGAT1",
            "MGAT4A",
            "MID1",
            "MLL",
            "MOAP1",
            "MPP6",
            "MPPED2",
            "MRPL13",
            "MTA2",
            "MTBP",
            "MYF6",
            "MYH1",
            "MYH10",
            "MYO18A",
            "NAGLU",
            "NAPB",
            "NAV2",
            "NAV3",
            "NCDN",
            "NDNF",
            "NDST4",
            "NDUFS4",
            "NEK1",
            "NEK2",
            "NFATC4",
            "NFYB",
            "NMI",
            "NMT1",
            "NR2F1",
            "NRG1",
            "NTRK2",
            "NUP54",
            "NXPH4",
            "OMA1",
            "OMG",
            "OR2L13",
            "OTX2",
            "PACRG",
            "PAPD5",
            "PARK2",
            "PART1",
            "PCDH17",
            "PCDH18",
            "PCF11",
            "PCYT1B",
            "PDGFB",
            "PDGFRA",
            "PDLIM2",
            "PDS5B",
            "PDZRN4",
            "PFN2",
            "PHC2",
            "PHEX",
            "PHF1",
            "PHF15",
            "PHF6",
            "PHOX2B",
            "PLAGL2",
            "PLEC",
            "PLEKHM1",
            "PLP2",
            "PMCH",
            "PMCHL1",
            "PODXL2",
            "POFUT1",
            "POU2AF1",
            "POU4F1",
            "PPAP2B",
            "PPP1R9B",
            "PPP2R3A",
            "PPP2R4",
            "PPP2R5E",
            "PPP3CA",
            "PRELP",
            "PRKCG",
            "PRKCQ",
            "PROK2",
            "PTH1R",
            "PXN",
            "R3HDM1",
            "RAB30",
            "RAB5B",
            "RAB5C",
            "RAPGEF4",
            "RBMS3",
            "RGS17",
            "RNF146",
            "ROBO4",
            "ROR1",
            "RPLP0",
            "RTN1",
            "RUFY3",
            "S1PR2",
            "SCN3B",
            "SCN5A",
            "SCN8A",
            "SCOC",
            "SDCBP",
            "SEMA6D",
            "SEPT7",
            "SESN3",
            "SGCD",
            "SH2D6",
            "SHC3",
            "SHCBP1L",
            "SIPA1",
            "SIRPA",
            "SLC26A6",
            "SLC4A1",
            "SLC6A1",
            "SMARCA2",
            "SNX9",
            "SORBS2",
            "SOX12",
            "SOX21",
            "SOX30",
            "SOX5",
            "SPOCK2",
            "SPTLC2",
            "SRGAP2",
            "SRSF8",
            "SSBP2",
            "ST7L",
            "STAC3",
            "STAG1",
            "STAG2",
            "STC2",
            "STRN3",
            "STRN4",
            "TAS1R2",
            "TEF",
            "TFAP4",
            "TFDP2",
            "TM2D3",
            "TMEM182",
            "TMEM27",
            "TMEM69",
            "TMSB4X",
            "TMSB4XP1",
            "TMSL3",
            "TMSL6",
            "TNFAIP8",
            "TNS1",
            "TNXB",
            "TP53INP2",
            "TRDN",
            "TREML1",
            "TRIM28",
            "TRIM68",
            "TRIM8",
            "TRIML1",
            "TRPS1",
            "TSC22D3",
            "TSPAN7",
            "TSPY26P",
            "TSSK3",
            "TTC17",
            "TUSC2",
            "UBE2W",
            "UBXN10",
            "USP1",
            "VDR",
            "VIP",
            "VKORC1L1",
            "VWA5A",
            "WBP1",
            "WNT2B",
            "WT1",
            "WT1-AS",
            "XRCC1",
            "ZADH2",
            "ZBTB11",
            "ZFP91",
            "ZFPM2",
            "ZIC1",
            "ZIC4",
            "ZMAT3",
            "ZNF238",
            "ZNF296",
            "ZNF503",
            "ZNF521",
            "ZNF524",
            "ZNF654",
            "ZNF687",
            "ZNF710"
         ]
      ],
      "elementType":"genes",
      "organism":"human",
      "queryType":"geneCheck",
      "symbolType":"symbol"
   }
}